Plant Transcription Factor Database
Previous version: v3.0
Brassica napus
EIL Family
Species TF ID Description
GSBRNA2T00000783001EIL family protein
GSBRNA2T00001316001EIL family protein
GSBRNA2T00003173001EIL family protein
GSBRNA2T00009271001EIL family protein
GSBRNA2T00026202001EIL family protein
GSBRNA2T00028229001EIL family protein
GSBRNA2T00029557001EIL family protein
GSBRNA2T00038285001EIL family protein
GSBRNA2T00049063001EIL family protein
GSBRNA2T00051968001EIL family protein
GSBRNA2T00066199001EIL family protein
GSBRNA2T00068988001EIL family protein
GSBRNA2T00079262001EIL family protein
GSBRNA2T00085793001EIL family protein
GSBRNA2T00088016001EIL family protein
GSBRNA2T00103449001EIL family protein
GSBRNA2T00122339001EIL family protein
GSBRNA2T00129740001EIL family protein
GSBRNA2T00134618001EIL family protein
GSBRNA2T00137324001EIL family protein
GSBRNA2T00138800001EIL family protein
GSBRNA2T00143537001EIL family protein
GSBRNA2T00154170001EIL family protein
EIL Family Introduction

The gaseous phytohormone ethylene regulates various processes related to growth, development, and stress response of higher plants. A largely linear pathway of ethylene signaling was revealed by a number of molecular genetic studies. In the pathway, Ethylene-insensitive3 (EIN3) and EIN3-like (EIL) proteins are the key transcription factors. The EIN3/EIL proteins were shown to regulate expression of the GCC-box-binding transcription factors, ethylene-response factors. It is known that the phenotype of the Arabidopsis thaliana EIN3 (AtEIN3)-deficient mutants, e.g. long seedlings in the presence of ethylene or its precursor, is suppressed by overexpression of Arabidopsis EIL1 (AtEIL1) or EIL2 (AtEIL2), indicating the functional equivalence of these proteins.

In the present study, a region corresponding to the major DBD of the EIN3/EIL transcription factor family, which is the key factor in the ethylene signaling, was identified. The isolated domain exists in a monomeric form and retained the sequence specificity for the DNA binding. The structure determined by NMR spectroscopy consists of five alpha-helices, packing into a novel fold dissimilar to known DBDs. An NMR titration analysis suggested that a region including the key mutation site, ein3-3 site, was shown to be involved in DNA binding.

Yamasaki K, Kigawa T, Inoue M, Yamasaki T, Yabuki T, Aoki M, Seki E, Matsuda T, Tomo Y, Terada T, Shirouzu M, Tanaka A, Seki M, Shinozaki K, Yokoyama S.
Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3.
J Mol Biol, 2005. 348(2): p. 253-64.
PMID: 15811366